6,727 research outputs found

    A Dagger Through the Heartland: The Louisville & Nashville Railroad in the Civil War

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    The Civil War was a defining moment in American history. What began as a sectional debate over states’ rights transformed itself into a bloody odyssey that would alter the national character itself. Within the wide scope of this conflict, scholars have sought to answer the multifaceted question of how the Union triumphed, often citing the proficient management of the railways as a key contribution to victory. Within this logistical network of rails, the Louisville & Nashville Railroad served as a vital mode of transportation for supplies and troop mobility through the heartland states of Kentucky and Tennessee. The Union exploited this advantage, thus making the Louisville & Nashville Railroad a case study in the field of Military History of successful: defensive strategy, offensive strategy, tactical efficiency and establishment of secure logistical lines. Doing so helped them secure the strategically important border state of Kentucky, which in turn became a launching pad into Tennessee and ultimately, the Deep South itself. Hence, the Louisville & Nashville Railroad significantly helped the Union win the Civil War

    Path, theme and narrative in open plan exhibition settings

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    Three arguments are made based on the analysis of science exhibitions. First,sufficiently refined techniques of spatial analysis allow us to model the impact oflayout upon visitors' paths, even in moderately sized open plans which allow almostrandom patterns of movement and relatively unobstructed visibility. Second, newlydeveloped or adapted techniques of analysis allow us to make a transition frommodeling the mechanics of spatial movement (the way in which movement is affectedby the distribution of obstacles and boundaries), to modeling the manner in whichmovement might register additional aspects of visual information. Third, theadvantages of such purely spatial modes of analysis extend into providing us with asharper understanding of some of the pragmatic constrains within which exhibitioncontent is conceived and designed

    Efficacy of Electrical Stimulation Intervention in Treating Adults with Dysphagia: A Systematic Review

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    Purpose: Dysphagia is a term used for a swallowing disorder resulting from problems with the oral cavity, pharynx, esophagus, or gastroesophageal junction. Dysphagia can have significant impacts on an individual’s quality of life and statistics suggest that nearly 15 million adults in the United States present with swallowing disorders. Common medical complications associated with dysphagia are malnutrition, dehydration, aspiration pneumonia, and even death. Traditional dysphagia treatment (TDT) for adults currently consists of diet modification, compensatory strategies involving postural adjustments, and swallowing exercises to strengthen musculature. The objective of this systematic review is to determine whether electrical stimulation (ES) improves swallowing function in adults with dysphagia. Methodology: Four indexed databases were searched to obtain studies pertaining to the use of ES in dysphagia treatment and its success. Application of inclusionary and exclusionary criteria narrowed the results and relevant studies were selected for this systematic review. Studies were also hand-selected and appraised for validity to ensure minimal bias. Results: Results of the selected studies revealed varying statistically significant effects of ES as a treatment for adults with dysphagia. However, many studies suggest ES is most effective in producing positive outcomes when coupled with TDT. Conclusion: The results of the systematic review suggest efficacy of ES is highest when it is used in conjunction with TDT. Studies with statistically significant results reported on only a minor improvement with ES. None of the studies reported negative outcomes related to ES. Additional research is needed to determine overall efficacy of ES as an evidence-based intervention for adults with dysphagia resulting from various etiologies.https://scholarworks.uvm.edu/csdms/1005/thumbnail.jp

    Purple People Eater Words

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    Peter Newby\u27s November 1995 Word Ways article The Anglo-American Hyphen arrived in the same mail until the 2 Dec 1995 issue of Science News. In the Biology column of the latter (page 178), this headline appeared: A TREATMENT PLANT-FISH HATCHERY IN ONE -- reminiscent, perhaps, of a medical facility for plant-fish. But since Providence has provided two symbols to clarify such ambiguities, the following is better: A TREATMENT-PLANT/FISH-HATCHERY IN ONE. With loyal fealty, the article followed the style of its title. It began with a 21 year-word/single-sentence paragraph, almost half of which was a 10-word name: East Chicago Sanitary District Wastewater Treatment Plan near Lake Michigan

    Proper Names, Improper Uses

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    Leonard R. N. Ashley presented a quiz titled The Proper Name in the Proper Use in the February 1995 issue of Word Ways. I worked it. I did my best, and although my answers differ somewhat from Ashley\u27s anyone who has (or has had) a teenage daughter and/or son will surely agree that my answers come as close to the mark (whoever she is) as Ashley\u27s

    New Measurements of High-Momentum Nucleons and Short-Range Structures in Nuclei

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    We present new measurements of electron scattering from high-momentum nucleons in nuclei. These data allow an improved determination of the strength of two-nucleon correlations for several nuclei, including light nuclei where clustering effects can, for the first time, be examined. The data also include the kinematic region where three-nucleon correlations are expected to dominate

    Neighbourhood greenspace is associated with a slower decline in physical activity in older adults: A prospective cohort study

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    Maintaining physical activity in later life is important for maintaining health and function. Activity outdoors, such as walking, jogging and cycling, may provide an accessible, sociable and practical solution, but maintaining outdoor mobility may be a challenge in later life. Providing green environments which are supportive of physical activity may facilitate this, yet research into how greenspace could be best used is inconclusive. This study evaluates the role of greenspace in protecting against decline in physical activity over time in older adults. Data from the European Prospective Investigation of Cancer Norfolk, UK, cohort 1993–2009 (N=15,672) was used. Linear regression modelling was used to examine the association between exposure to greenspace in the home neighbourhood and change in overall, recreational and outdoor physical activity measured in terms of metabolic equivalent cost (MET) in hours/week. Mediation analysis was conducted to assess if dog walking explained the relationship between greenspace and physical activity change. Models were adjusted for known and hypothesised confounders. People living in greener neighbourhoods experienced less of a decline in physical activity than those living in less green areas. Comparing change for those living in the greenest versus least green quartiles, participants showed a difference in overall physical activity of 4.21 MET hours/week (trend P=0.001), adjusted for baseline physical activity, age, sex, BMI, social class and marital status. This difference was 4.03 MET hours/week for recreational physical activity (trend P<0.001) and 1.28 MET hours/week for outdoor physical activity (trend P=0.007). Dog walking partially mediated the association between greenspace and physical activity change, by 22.6% for overall, 28.1% for recreational and 50.0% for outdoor physical activity (all P<0.001). Greenspace in the home neighbourhood may be protective against decline in physical activity among older people as they age. Dog walking is a potential mechanism in this relationship, and warrants further investigation as a way of maintaining physical activity in later life.This work was supported by the Centre for Diet and Activity Research (CEDAR), a UKCRC Public Health Research Centre of Excellence. Funding from Cancer Research UK, the British Heart Foundation, the Economic and Social Research Council, the Medical Research Council, the National Institute for Health Research, and the Wellcome Trust, under the auspices of the UK Clinical Research Collaboration, is gratefully acknowledged. The corresponding author was supported by the Medical Research Council, grant number MR/K025147/1. The study was also supported by the Medical Research Council, grant numbers MC_UU_12015/1 and MC_UU_12015/4

    Lifestyle intervention in individuals with impaired glucose regulation affects Caveolin-1 expression and DNA methylation

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    © 2020, © 2020 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. Aims: We investigated whether a lifestyle intervention could influence expression and DNA methylation of diabetes-related genes in patients with impaired glucose regulation (IGR), the results were compared to bariatric surgery, considering it an intensive change. Methods: Twenty participants with IGR had adipose tissue biopsy and blood collected pre- and post-lifestyle (6 months) intervention; 12 obese patients had subcutaneous fat taken before and after bariatric surgery. RNA/DNA was extracted from all samples and underwent qPCR. DNA was bisulphite converted and 12 CpG sites of Caveolin-1 (CAV1) promoter were pyrosequenced. Results: lifestyle intervention resulted in opposite direction changes in fat tissue and blood for CAV1 expression and DNA methylation and these changes were correlated between tissues, while no significative differences were found in CAV1 expression after bariatric surgery. Conclusions: Our findings suggest a role for CAV1 in modulating adipocyte function as a consequence of lifestyle changes, as exercises and diet. These results may provide insights into new therapeutic targets for diabetes prevention
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